SCHEMBL8614873

SCHEMBL8614873

C(CCN1CCNCC1)CN1CCNCC1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 3/20 0.70
POLB P06746 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SIGMAR1 Q99720 2/20 0.54
HRH3 Q9Y5N1 2/20 0.48
HSD17B10 Q99714 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
GNAO1 P09471 5/20 0.45
GNAI3 P08754 4/20 0.45
GNAI1 P63096 4/20 0.45
KDM1A O60341 1/20 0.44
RAD52 P43351 1/20 0.43
HRH2 P25021 1/20 0.42
HRH1 P35367 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11721752 0.97 CXCR4 (0.74) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
SCHEMBL21569302 0.97 CXCR4 (0.74) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
Hydrochloric Acid SCHEMBL5570648 0.97 CXCR4 (0.67) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
SCHEMBL1841507 0.97 CXCR4 (0.74) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
SCHEMBL11726023 0.97 CXCR4 (0.74) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
SCHEMBL6657549 0.94 CXCR4 (0.78) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
Hydrochloric Acid SCHEMBL5570696 0.94 CXCR4 (0.71) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
SCHEMBL993010 0.94 CXCR4 (0.73) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
SCHEMBL24533550 0.92 CXCR4 (0.75) CXCR4POLBSMN1; SMN2SIGMAR1HRH3
Hydrochloric Acid SCHEMBL5570598 0.91 CXCR4 (0.70) CXCR4POLBSMN1; SMN2SIGMAR1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5612448-A POLYAMIDES WITH HIGH STRENGTH AND FLEXIBILITY UNION CAMP CORPORATION (US) 1997-03-18 US claimed
EP-0721473-A4 CURABLE ADHESIVE COMPOSITIONS CONTAINING POLYAMIDE RESINS UNION CAMP CORP (US) 1996-09-25 EP claimed
EP-0721473-A1 CURABLE ADHESIVE COMPOSITIONS CONTAINING POLYAMIDE RESINS Union Camp Corporation (US) 1996-07-17 EP claimed
EP-0442700-B1 Two-component curable hot-melt resin compositions UNION CAMP CORP (US) 1996-01-03 EP claimed
WO-1995009189-A1 CURABLE ADHESIVE COMPOSITIONS CONTAINING POLYAMIDE RESINS UNION CAMP CORPORATION (US) 1995-04-06 WO claimed
US-5385986-A Improved cohesion, adhesion, ductility, flexibility; heat, solvent and moisture resistance; curable UNION CAMP CORPORATION (US) 1995-01-31 US claimed
EP-0442700-A2 Two-component curable hot-melt resin compositions UNION CAMP CORPORATION (US) 1991-08-21 EP claimed
EP-0441545-A1 Two-component curable hot-melt resin compositions Union Camp Corporation (US) 1991-08-14 EP claimed
EP-0847423-A4 METHOD OF IMPROVING BLOCK RESISTANCE OF ADHESIVE COMPOSITIONS 1998-09-09 EP disclosed
EP-0847423-A1 METHOD OF IMPROVING BLOCK RESISTANCE OF ADHESIVE COMPOSITIONS UNION CAMP CORPORATION (US) 1998-06-17 EP disclosed
US-5612448-A POLYAMIDES WITH HIGH STRENGTH AND FLEXIBILITY UNION CAMP CORPORATION (US) 1997-03-18 US disclosed
WO-1996041837-A9 METHOD OF IMPROVING BLOCK RESISTANCE OF ADHESIVE COMPOSITIONS 1997-02-13 WO disclosed
WO-1996041837-A1 METHOD OF IMPROVING BLOCK RESISTANCE OF ADHESIVE COMPOSITIONS UNION CAMP CORPORATION (US) 1996-12-27 WO disclosed
EP-0721473-A4 CURABLE ADHESIVE COMPOSITIONS CONTAINING POLYAMIDE RESINS UNION CAMP CORP (US) 1996-09-25 EP disclosed
WO-1995009189-A1 CURABLE ADHESIVE COMPOSITIONS CONTAINING POLYAMIDE RESINS UNION CAMP CORPORATION (US) 1995-04-06 WO disclosed
US-5385986-A Improved cohesion, adhesion, ductility, flexibility; heat, solvent and moisture resistance; curable UNION CAMP CORPORATION (US) 1995-01-31 US disclosed
US-5296557-A Consisting of specified thermoplastic polyamide, epoxy resin UNION CAMP CORPORATION (US) 1994-03-22 US disclosed
EP-0442700-A2 Two-component curable hot-melt resin compositions UNION CAMP CORPORATION (US) 1991-08-21 EP disclosed
EP-0441545-A1 Two-component curable hot-melt resin compositions Union Camp Corporation (US) 1991-08-14 EP disclosed
US-4059549-A POLYURETHANE, ENAMINE SCHERING AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed