SCHEMBL8614944

SCHEMBL8614944

CO[C@@H]1OC(O)(CO)[C@H](O)[C@H](O)[C@H]1OC

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MGAM O43451 4/20 0.33
SI P14410 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9167213 1.00 MEN1 (0.41) MEN1KMT2AMGAMSI
SCHEMBL9165078 1.00 MEN1 (0.41) MEN1KMT2AMGAMSI
SCHEMBL9744359 1.00 MEN1 (0.41) MEN1KMT2AMGAMSI
SCHEMBL882792 0.87 MEN1 (0.41) MEN1KMT2AMGAMSI
SCHEMBL12135599 0.87 MEN1 (0.41) MEN1KMT2AMGAMSI
SCHEMBL5553005 0.87 MEN1 (0.41) MEN1KMT2AMGAMSI
SCHEMBL9168872 0.87 MEN1 (0.38) MEN1KMT2A
SCHEMBL9855305 0.85 MEN1 (0.43) MEN1KMT2AMGAMSI
SCHEMBL9165994 0.85 MEN1 (0.43) MEN1KMT2AMGAMSI
SCHEMBL9745095 0.85 MEN1 (0.43) MEN1KMT2AMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0607245-B1 CHOLESTEROL LOWERING COMPOUNDS AND PROCESS FOR MAKING THEM PROCTER & GAMBLE (US) 1998-04-22 EP disclosed
US-5591836-A STEROL 5-C-HYDROXYMETHYL GLYCOSIDE THE PROCTER & GAMBLE COMPANY (US) 1997-01-07 US disclosed
EP-0341063-B1 Process for preparing 5-C-hydroxymethyl aldohexose-based compounds PROCTER & GAMBLE (US) 1994-03-16 EP disclosed
US-5106967-A Esterified 5-C-hydroxymethyl hexose; bonding to mono- and disaccharides; foods, baked goods, beverages THE PROCTER & GAMBLE COMPANY (US) 1992-04-21 US disclosed
US-5104797-A Oxidation of a D-aldohexose derivative using an oxidase followed by reacting the aqueous solution with formaldehyde in the presence of a base; purification THE PROCTER & GAMBLE COMPANY (US) 1992-04-14 US disclosed
US-5064672-A 5-C-hydroxymethyl hexoses, bulking THE PROCTER & GAMBLE COMPANY (US) 1991-11-12 US disclosed
US-5041541-A 5-C-Hydroxymethylhexose Compounds THE PROCTER & GAMBLE COMPANY (US) 1991-08-20 US disclosed
EP-0341062-A2 Functional sugar substitutes with reduced calories THE PROCTER & GAMBLE COMPANY (US) 1989-11-08 EP disclosed
EP-0341063-A2 Process for preparing 5-C-hydroxymethyl aldohexose-based compounds THE PROCTER & GAMBLE COMPANY (US) 1989-11-08 EP disclosed