Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851120 | 0.92 | PRKAA2 (0.47) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851914 | 0.89 | PRSS1 (0.50) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851681 | 0.86 | PRKAA2 (0.45) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL852428 | 0.86 | CHRM4 (0.43) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL852002 | 0.85 | F2 (0.46) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851247 | 0.84 | F2 (0.46) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851102 | 0.83 | F2 (0.42) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851136 | 0.82 | PRKAA2 (0.47) | PRKAA2GPR119CCNCCDK8NAMPT | |
| SCHEMBL851246 | 0.81 | PRSS1 (0.45) | F2PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL851532 | 0.81 | PRSS1 (0.51) | F2PRSS1PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |