SCHEMBL8616115

SCHEMBL8616115

Fc1cc(-c2ccc(OCc3ccccc3)cc2)ccc1-c1ccc(Br)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 2/20 0.56
MCL1 Q07820 2/20 0.52
MAOB P27338 3/20 0.48
MRGPRX4 Q96LA9 1/20 0.47
PTGES O14684 2/20 0.46
AR P10275 1/20 0.46
FFAR1 O14842 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
APP P05067 1/20 0.45
S1PR1 P21453 1/20 0.45
S1PR3 Q99500 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
PTGS1 P23219 1/20 0.45
SLC6A2 P23975 1/20 0.45
CYP2C19 P33261 1/20 0.45
PTGS2 P35354 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HIF1A Q16665 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8612999 1.00 GSTP1 (0.56) GSTP1MCL1MAOBMRGPRX4PTGES
SCHEMBL8617910 0.94 GSTP1 (0.56) GSTP1MCL1MAOBMRGPRX4PTGES
SCHEMBL8613938 0.94 GSTP1 (0.52) GSTP1MCL1MAOBMRGPRX4PTGES
SCHEMBL8615440 0.93 GSTP1 (0.55) GSTP1MCL1MAOBMRGPRX4PTGES
SCHEMBL8612484 0.93 GSTP1 (0.51) GSTP1MCL1MAOBMRGPRX4PTGES
SCHEMBL8617339 0.93 GSTP1 (0.57) GSTP1MCL1MAOBMRGPRX4PTGES
SCHEMBL8616016 0.93 GSTP1 (0.54) GSTP1MCL1MAOBMRGPRX4PTGES
SCHEMBL8616187 0.90 GSTP1 (0.55) GSTP1MCL1MAOBPTGESFFAR1
SCHEMBL8616652 0.89 GSTP1 (0.50) GSTP1MCL1MAOBPTGESFFAR1
SCHEMBL8613447 0.89 MAOB (0.55) GSTP1MCL1MAOBPTGESS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665836-B1 BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS HOECHST AG (DE) 1998-04-29 EP disclosed
WO-1994010152-A1 BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1994-05-11 WO disclosed