SCHEMBL8616566

Oc1ccc(OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ESR2	Q92731	5/20	0.39

▸	ESR1	P03372	4/20	0.39

▸	MEN1	O00255	2/20	0.39

▸	KMT2A	Q03164	2/20	0.39

▸	KDM4E	B2RXH2	1/20	0.39

▸	LTA4H	P09960	2/20	0.34

▸	NR1H2	P55055	1/20	0.34

▸	BAX	Q07812	1/20	0.34

▸	KIF11	P52732	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8612601	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL8614899	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL8613624	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL8616470	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL8614487	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL8616433	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL8416038	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL1237150	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL8616420	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E
SCHEMBL8615345	1.00	ESR2 (0.39)	ESR2ESR1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0837085-A1	POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM	IDEMITSU KOSAN COMPANY LIMITED (JP)	1998-04-22	—	—	EP	disclosed