Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701340 | 0.98 | KDM4E (0.57) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| SCHEMBL1726737 | 0.98 | KDM4E (0.57) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| SCHEMBL5843494 | 0.98 | KDM4E (0.57) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| Hydrochloric Acid SCHEMBL5843429 | 0.96 | GLA (0.56) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| SCHEMBL1358701 | 0.94 | KDM4E (0.61) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| Hydrochloric Acid SCHEMBL11543248 | 0.92 | GLA (0.60) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| SCHEMBL951890 | 0.88 | GLA (0.64) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| SCHEMBL30887599 | 0.86 | GLA (0.57) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| Hydrochloric Acid SCHEMBL6044162 | 0.86 | GLA (0.68) | KDM4EGAASMN1; SMN2KEAP1GLA | |
| SCHEMBL1831207 | 0.85 | EPHX2 (0.53) | KDM4EGAASMN1; SMN2KEAP1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036895-B1 | HSP90 INHIBITOR | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2013-01-16 | — | — | EP | claimed |
| EP-3801501-A1 | ESTROGEN RECEPTOR INHIBITORS AND USES THEROF | The Regents of the University of California (US) | 2021-04-14 | — | — | EP | disclosed |
| EP-3224230-A1 | ESTROGEN RECEPTOR MODULATORS | The Regents of The University of California (US) | 2017-10-04 | — | — | EP | disclosed |
| WO-2016085825-A1 | ESTROGEN RECEPTOR MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-02 | — | — | WO | disclosed |
| EP-0615525-B1 | HYDROPHILIC POLY-(N-SUBSTITUTED)ACRYLAMIDE GELS AND THEIR USE IN ELECTROKINETIC AND CHROMATOGRAPHIC METHODOLOGIES | RIGHETTI PIER GIORGIO (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-5470916-A | Formulations for polyacrylamide matrices in electrokinetic and chromatographic methodologies | RIGHETTI PIER G (IT) | 1995-11-28 | — | — | US | disclosed |
| EP-0615525-A1 | HYDROPHILIC POLY-(N-SUBSTITUTED)ACRYLAMIDE GELS AND THEIR USE IN ELECTROKINETIC AND CHROMATOGRAPHIC METHODOLOGIES | RIGHETTI, Pier Giorgio (IT) | 1994-09-21 | — | — | EP | disclosed |
| WO-1993011174-A1 | NEW FORMULATIONS FOR POLYACRYLAMIDE MATRICES IN ELECTROKINETIC AND CHROMATOGRAPHIC METHODOLOGIES | RIGHETTI PIER GIORGIO (IT) | 1993-06-10 | — | — | WO | disclosed |