Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687699 | 0.76 | CYP3A4 (0.41) | KDM4EPKM | |
| SCHEMBL8614886 | 0.73 | KDM4E (0.32) | KDM4EPKM | |
| Hydrochloric Acid SCHEMBL8614293 | 0.72 | KDM4E (0.31) | KDM4EPKM | |
| SCHEMBL9490039 | 0.69 | KDM4E (0.42) | KDM4EPKM | |
| SCHEMBL8616899 | 0.68 | CNR1 (0.33) | KDM4EPKM | |
| SCHEMBL8613498 | 0.67 | KDM4E (0.32) | KDM4EPKM | |
| SCHEMBL9270037 | 0.66 | KDM4E (0.34) | KDM4EPKM | |
| SCHEMBL9049390 | 0.66 | KDM4E (0.31) | KDM4EPKM | |
| SCHEMBL9270043 | 0.66 | KDM4E (0.34) | KDM4EPKM | |
| SCHEMBL8738019 | 0.63 | CA12 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731335-A | NERVOUS SYSTEM DISORDERS; STROKE; ANTIISCHEMIC AGENTS; COGNITION ACTIVATORS | ASTRA AKTIEBOLAG (SE) | 1998-03-24 | — | — | US | disclosed |
| US-5607956-A | TREATMENT OF NEURODEGENERATIVE DISORDERS SUCH AS CEREBRAL ISCHEMIA, ALZHEIMER'S DISEASE | ASTRA AKTIEBOLAG (SE) | 1997-03-04 | — | — | US | disclosed |
| WO-1995001979-A1 | NOVEL (1-HETEROAZOLYL-1-HETEROCYCLYL)ALKANE DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE AGENTS | ASTRA AKTIEBOLAG (SE) | 1995-01-19 | — | — | WO | disclosed |