Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PYGL | P06737 | 3/20 | 0.48 |
| ▸ | BRAF | P15056 | 6/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | PNLIP | P16233 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326642 | 0.98 | GCGR (0.54) | GCGRTDP1PYGLBRAFKDR | |
| SCHEMBL9326325 | 0.89 | MEN1 (0.48) | TDP1BRAFKDRPNLIPMEN1 | |
| Flufenoxuron SCHEMBL29413952 | 0.87 | MEN1 (0.52) | BRAFKDRMEN1KMT2AFFAR1 | |
| Flufenoxuron SCHEMBL8407576 | 0.87 | MEN1 (0.52) | BRAFKDRMEN1KMT2AFFAR1 | |
| Flufenoxuron SCHEMBL27798 | 0.87 | MEN1 (0.52) | BRAFKDRMEN1KMT2AFFAR1 | |
| SCHEMBL8659897 | 0.86 | GCGR (0.72) | GCGRTDP1PNLIPFFAR1 | |
| SCHEMBL9325616 | 0.86 | MEN1 (0.51) | TDP1BRAFKDRMEN1TTR | |
| SCHEMBL10338942 | 0.85 | BRAF (0.46) | TDP1BRAFKDRMEN1TTR | |
| Flufenoxuron SCHEMBL28899111 | 0.85 | MEN1 (0.50) | BRAFKDRMEN1KMT2A | |
| SCHEMBL9325879 | 0.84 | GCGR (0.69) | GCGRTDP1PNLIPMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854288-A | Use of benzoylureas for controlling house dust mites | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-29 | — | — | US | disclosed |
| EP-0729301-A1 | USE OF BENZOYLUREAS FOR CONTROLLING HOUSE DUST MITES | Hoechst Schering AgrEvo GmbH (DE) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995013703-A1 | USE OF BENZOYLUREAS FOR CONTROLLING HOUSE DUST MITES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-05-26 | — | — | WO | disclosed |