Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30342247 | 0.89 | TDP1 (0.55) | MEN1KMT2AMAPK1MAPTTDP1 | |
| SCHEMBL187588 | 0.89 | TDP1 (0.55) | MEN1KMT2AMAPK1MAPTTDP1 | |
| SCHEMBL28313589 | 0.89 | TDP1 (0.55) | MEN1KMT2AMAPK1MAPTTDP1 | |
| Hydrogen Sulfide SCHEMBL28338492 | 0.88 | TDP1 (0.53) | MEN1KMT2AMAPK1MAPTTDP1 | |
| SCHEMBL29747008 | 0.88 | MAPK1 (0.53) | MEN1KMT2AMAPK1MAPTTDP1 | |
| SCHEMBL6810312 | 0.86 | MEN1 (0.52) | MEN1KMT2AMAPK1MAPTTDP1 | |
| SCHEMBL4436535 | 0.86 | MEN1 (0.52) | MEN1KMT2AMAPK1MAPTTDP1 | |
| SCHEMBL27372853 | 0.85 | MAPK1 (0.38) | MEN1KMT2AMAPK1MAPTTDP1 | |
| SCHEMBL2241440 | 0.84 | MEN1 (0.42) | MEN1KMT2AMAPK1MAPTTDP1 | |
| SCHEMBL27468058 | 0.83 | MYC (0.48) | MEN1KMT2AMAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101312985-B | Polynucleotide containing phosphate mimetic | HOFFMAN-LA ROCHE LTD. (CH) | 2015-08-19 | — | — | CN | disclosed |
| CN-101312985-A | Polynucleotide containing a phosphate mimetic | HOFFMANN LA ROCHE (CH) | 2008-11-26 | — | — | CN | disclosed |
| EP-0361284-B1 | T cell growth factor | LUDWIG INST CANCER RES (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5750377-A | SYNERGISTIC WITH INTERLEUKINS | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | disclosed |
| US-5587302-A | ISOLATED POLYNUCLEOTIDES ENCODES POLYPEPTIDE INTERLEUKINS | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1996-12-24 | — | — | US | disclosed |
| EP-0466854-A4 | T CELL GROWTH FACTOR | — | 1993-03-31 | — | — | EP | disclosed |
| US-5157112-A | Supports interleukin-2 and interleukin-4 independent growth of helper T cells | LUDWIG INSTITUTE FOR CANCER RESEARCH (CH) | 1992-10-20 | — | — | US | disclosed |
| EP-0466854-A1 | T CELL GROWTH FACTOR | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1992-01-22 | — | — | EP | disclosed |
| WO-1991010738-A1 | T CELL GROWTH FACTOR | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-07-25 | — | — | WO | disclosed |
| EP-0361284-A2 | T cell growth factor | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 1990-04-04 | — | — | EP | disclosed |
| US-4828979-A | BIOTINYLATED | LIFE TECHNOLOGIES, INC. (US) | 1989-05-09 | — | — | US | disclosed |