Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613438 | 1.00 | KDM1A (0.43) | KDM1ARAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL319757 | 0.94 | KDM1A (0.47) | KDM1ARAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL30782654 | 0.94 | KDM1A (0.47) | KDM1ARAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8613441 | 0.93 | KDM1A (0.40) | KDM1ARAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8613734 | 0.88 | FEN1 (0.41) | KDM1ARAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL8612028 | 0.85 | FEN1 (0.40) | KDM1ARAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL26604918 | 0.85 | SMN1; SMN2 (0.44) | KDM1ARAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8617918 | 0.84 | ERN1 (0.46) | KDM1ARAB9ASMN1; SMN2MRGPRX4FFAR1 | |
| SCHEMBL8617922 | 0.83 | KDM1A (0.40) | KDM1ARAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL8615456 | 0.83 | ERN1 (0.45) | KDM1ARAB9ASMN1; SMN2MRGPRX4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |