Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.55 |
| ▸ | FNTB | P49356 | 15/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501363 | 0.95 | FNTA (0.60) | FNTAFNTBMEN1KMT2APGGT1B | |
| Trifluoroacetic Acid SCHEMBL8456093 | 0.94 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8452831 | 0.93 | FNTA (0.55) | FNTAFNTBMEN1KMT2APGGT1B | |
| Trifluoroacetic Acid SCHEMBL8455766 | 0.91 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8454195 | 0.91 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8454005 | 0.90 | FNTA (0.56) | FNTAFNTBMEN1KMT2APGGT1B | |
| Trifluoroacetic Acid SCHEMBL8452838 | 0.90 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL8452331 | 0.90 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL9083554 | 0.90 | FNTA (0.58) | FNTAFNTBMEN1KMT2APGGT1B | |
| Trifluoroacetic Acid SCHEMBL8452329 | 0.90 | FNTA (0.58) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820445-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996030343-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |