Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641460 | 0.83 | SMYD2 (0.33) | SMN1; SMN2CYP3A4HTT | |
| SCHEMBL19689304 | 0.80 | SMYD2 (0.36) | ALDH1A1GAASMN1; SMN2CYP3A4HTT | |
| SCHEMBL25487136 | 0.80 | SMYD2 (0.34) | SMN1; SMN2CYP3A4HTT | |
| SCHEMBL4130523 | 0.78 | SMYD2 (0.36) | ALDH1A1GAASMN1; SMN2CYP3A4HTT | |
| SCHEMBL29235827 | 0.78 | SMYD2 (0.34) | SMN1; SMN2CYP3A4HTT | |
| SCHEMBL29235511 | 0.78 | SMYD2 (0.34) | SMN1; SMN2CYP3A4HTT | |
| SCHEMBL8612535 | 0.77 | SMYD2 (0.35) | SMN1; SMN2CYP3A4HTT | |
| SCHEMBL4119688 | 0.76 | SMYD2 (0.34) | SMN1; SMN2CYP3A4HTT | |
| SCHEMBL13596143 | 0.76 | SMYD2 (0.36) | KMT2AALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL29583645 | 0.76 | SMYD2 (0.36) | KMT2ASMN1; SMN2MEN1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052913-A2 | LEUKOTRIENE B4 ANTAGONISTS, IN PARTICULAR 3-OXA-TETRAHYDRONAPHTHALENE-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |