Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619377 | 1.00 | MRGPRX4 (0.54) | MRGPRX4TP53HTTHIF1ANPC1 | |
| SCHEMBL8618288 | 0.93 | TP53 (0.49) | MRGPRX4TP53HTTHIF1ANPC1 | |
| SCHEMBL8618293 | 0.93 | TP53 (0.49) | MRGPRX4TP53HTTHIF1ANPC1 | |
| SCHEMBL8617210 | 0.91 | MRGPRX4 (0.51) | MRGPRX4TP53HTTHIF1A | |
| SCHEMBL8617209 | 0.91 | MRGPRX4 (0.51) | MRGPRX4TP53HTTHIF1A | |
| SCHEMBL8645173 | 0.90 | MRGPRX4 (0.68) | MRGPRX4TP53HTTHIF1A | |
| SCHEMBL8645171 | 0.90 | MRGPRX4 (0.68) | MRGPRX4TP53HTTHIF1A | |
| SCHEMBL8369647 | 0.89 | HIF1A (0.50) | HTTHIF1ANPC1KDM4E | |
| SCHEMBL8589674 | 0.89 | HIF1A (0.50) | MRGPRX4HIF1AKDM4E | |
| SCHEMBL7543562 | 0.89 | HIF1A (0.50) | HTTHIF1ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |