Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617763 | 0.80 | HSP90AA1 (0.46) | HPGDKDM4ELMNANCEH1NR1I2 | |
| SCHEMBL7355150 | 0.79 | CA12 (0.43) | HPGDKDM4ELMNANCEH1ALDH1A1 | |
| SCHEMBL8624752 | 0.76 | HPGD (0.47) | HPGDKDM4ELMNANCEH1NR1I2 | |
| SCHEMBL8623668 | 0.76 | HPGD (0.47) | HPGDKDM4ELMNANCEH1NR1I2 | |
| SCHEMBL7173525 | 0.76 | IDO1 (0.49) | HPGDKDM4ELMNANCEH1ALDH1A1 | |
| SCHEMBL8619487 | 0.75 | KDM4E (0.37) | HPGDKDM4ELMNANCEH1ALDH1A1 | |
| SCHEMBL8621614 | 0.74 | HPGD (0.44) | HPGDKDM4ELMNANCEH1NR1I2 | |
| SCHEMBL8617880 | 0.74 | KDM4E (0.53) | HPGDKDM4ELMNANPSR1KMT2A | |
| SCHEMBL2116374 | 0.70 | KDM4E (0.43) | HPGDKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL10343358 | 0.70 | CNR1 (0.54) | HPGDKDM4ELMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |