Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 11/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623619 | 0.90 | HTR2A (0.47) | HTR2AHTR2CHTR2BUTS2RSLC6A2 | |
| SCHEMBL8618784 | 0.89 | HTR2A (0.58) | HTR2AHTR2CHTR2BSLC6A2SLC6A3 | |
| SCHEMBL8625124 | 0.89 | HTR2A (0.50) | HTR2AHTR2CHTR2BSLC6A2SLC6A3 | |
| SCHEMBL8620804 | 0.86 | FDFT1 (0.53) | SLC6A2SLC6A3FDFT1CNR1CNR2 | |
| SCHEMBL8623834 | 0.86 | FDFT1 (0.53) | SLC6A2SLC6A3FDFT1CNR1CNR2 | |
| SCHEMBL8623070 | 0.86 | FDFT1 (0.53) | SLC6A2SLC6A3FDFT1CNR1CNR2 | |
| SCHEMBL8625643 | 0.86 | FDFT1 (0.53) | SLC6A2SLC6A3FDFT1CNR1CNR2 | |
| SCHEMBL8619441 | 0.86 | SLC6A2 (0.56) | SLC6A2SLC6A3FDFT1CNR1CNR2 | |
| SCHEMBL8621289 | 0.86 | SLC6A2 (0.56) | SLC6A2SLC6A3FDFT1CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL7761818 | 0.85 | FDFT1 (0.52) | UTS2RSLC6A2SLC6A3FDFT1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777150-A | Substituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0611749-B1 | Substituted amic acid derivatives useful for treatment of arteriosclerosis | BANYU PHARMA CO LTD (JP) | 1997-10-22 | — | — | EP | disclosed |
| US-5606101-A | INTERMEDIATES FOR SQUALENE SYNTHASE INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0611749-A1 | Substituted amic acid derivatives useful for treatment of arteriosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |