Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 14/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622076 | 0.93 | SIRT2 (0.40) | ESR2CYP19A1SIRT2HSD17B3 | |
| SCHEMBL8625738 | 0.91 | SIRT2 (0.42) | CYP19A1SIRT2 | |
| SCHEMBL8622062 | 0.87 | SIRT2 (0.39) | ESR2HSD17B10CYP19A1SIRT2HSD17B3 | |
| SCHEMBL8852255 | 0.86 | ESR1 (0.33) | ESR2CYP19A1ESR1 | |
| SCHEMBL8622049 | 0.85 | SIRT2 (0.35) | ESR2HSD17B10CYP19A1SIRT2 | |
| SCHEMBL10581919 | 0.84 | SIRT2 (0.37) | ESR2HSD17B10CYP19A1SIRT2 | |
| SCHEMBL8622095 | 0.81 | SIRT2 (0.45) | CYP19A1SIRT2 | |
| SCHEMBL8622131 | 0.79 | SIRT2 (0.41) | CYP19A1SIRT2 | |
| SCHEMBL8621156 | 0.79 | SIRT2 (0.47) | CYP19A1SIRT2 | |
| SCHEMBL8624874 | 0.78 | SIRT2 (0.43) | CYP19A1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852221-A | Optically active β-aminoalkoxyborane complex | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5808098-A | REDUCING AGENT FROM AMINOALCOHOL | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0680484-B1 | OPTICALLY ACTIVE BETA-AMINOALKOXYBORANE COMPLEXES | NISSAN CHEMICAL IND LTD (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5786485-A | REACTING OPTICALLY ACTIVE BETA-AMINOALCOHOL WITH BORANE REAGENT TO PRODUCE OPTICALLY ACTIVE BETA-AMINOALKOXYBORANE COMPLEX | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5767277-A | REDUCING AGENT FOR A CARBONYL COMPOUND TO PRODUCE A 1,3-SYN-DIOL COMPOUND | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5739347-A | REDUCING AGENTS FOR DECARBONYLATION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5663348-A | REDUCTION OF DIKETONE WITH AMINOALKOXYBORANE COMPLEX TO FORM DIALCOHOL ESTER COMPOUND | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0680484-A1 | OPTICALLY ACTIVE $g(b)-AMINOALKOXYBORANE COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017079-A1 | OPTICALLY ACTIVE β-AMINOALKOXYBORANE COMPLEX | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-08-04 | — | — | WO | disclosed |