SCHEMBL8620643

SCHEMBL8620643

CCOC(=O)/C=C/C(=O)OC(C)CC(C)(C)OOC(C)(C)CC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.42
MAPT P10636 5/20 0.33
LMNA P02545 2/20 0.32
MDM2 Q00987 2/20 0.32
MDM4 O15151 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
MMP8 P22894 1/20 0.32
ATM Q13315 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TTR P02766 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8620650 1.00 HCAR2 (0.42) HCAR2MAPTLMNAMDM2MDM4
SCHEMBL8614142 0.92 HCAR2 (0.36) HCAR2LMNAALDH1A1
SCHEMBL8614138 0.92 HCAR2 (0.36) HCAR2LMNAALDH1A1
SCHEMBL8616799 0.91 HCAR2 (0.42) HCAR2MAPTLMNAMDM2MDM4
SCHEMBL8616792 0.91 HCAR2 (0.42) HCAR2MAPTLMNAMDM2MDM4
SCHEMBL8620557 0.87 HCAR2 (0.47) HCAR2
SCHEMBL8620554 0.87 HCAR2 (0.47) HCAR2
SCHEMBL20302202 0.81 HCAR2 (0.37) HCAR2LMNAALDH1A1
SCHEMBL8618741 0.81 HCAR2 (0.37) HCAR2LMNAALDH1A1
SCHEMBL8618736 0.81 HCAR2 (0.37) HCAR2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667339-B1 Novel unsaturated peroxides, polymeric peroxides derived therefrom and their uses ATOCHEM NORTH AMERICA ELF (US) 1998-05-06 EP disclosed
US-5494988-A FREE RADICAL INITIATORS AS MONOMERS; CROSSLINKING UNSATURATED POLYESTERS; ADDITION, GRAFT AND BLOCK POLYMERIZATION; COMPATIBILIZING BLENDS ELF ATOCHEM NORTH AMERICA, INC. (US) 1996-02-27 US disclosed
US-5489699-A USED AS FREE RADICAL GENERATOR, POLYMERIZING ETHYNICALLY UNSATURATED MONOMERS, CURING AGENT, RHEOLOGICAL MODIFIER,AND FOR GRAFTING AND COMPATIBILIZING POLYMER BLEND ELFATOCHEM NORTH AMERICA, INC. (US) 1996-02-06 US disclosed
US-5475072-A Curing; crosslinking; modifiying; grafting; compatibilizing ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-12 US disclosed
EP-0667339-A1 Novel unsaturated peroxides, polymeric derived therefrom and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-08-16 EP disclosed