SCHEMBL8620649

SCHEMBL8620649

C#CCO.[KH].[KH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9144 0.95
SCHEMBL5309104 0.95
SCHEMBL11569432 0.90
SCHEMBL11693501 0.90
Iodide SCHEMBL10929544 0.90
SCHEMBL31375345 0.90
Hydrochloric Acid SCHEMBL646495 0.90
SCHEMBL11578198 0.90
SCHEMBL6790136 0.90
SCHEMBL8380640 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1080267-C Preparation of intermediat of 19, 11 beta-bridge steroid SCHERING AG (DE) 2002-03-06 CN disclosed
CN-1061052-C 11 Beta-aromatic group-4-estraene and acid additive salt application in medicine SCHERING AG (DE) 2001-01-24 CN disclosed
CN-1057770-C Application of 19,11 beta-bridged sterodal compound in pharmaceutical working SCHERING AG (DE) 2000-10-25 CN disclosed
CN-1048499-C 11 beta-aryl-4-estrene pharmaceutical composition and process for preparing same SCHERING AG (DE) 2000-01-19 CN disclosed
US-5843931-A 6,7-modified 11β-aryl-4-oestrenes SHERING AKTIENGESELLSCHAFT (DE) 1998-12-01 US disclosed
CN-1039328-C D-high-(16-ene)-11 beta-aryl-4-estrene, preparing process and application in medicine SCHERING AG (DE) 1998-07-29 CN disclosed
CN-1141926-A Preparation of intermediat of 19, 11 beta-bridge steroid SCHERING AG (DE) 1997-02-05 CN disclosed
CN-1135488-A Application of 19,11 beta-bridged sterodal compound in pharmaceutical working SCHERING AG (DE) 1996-11-13 CN disclosed
CN-1133296-A 11 beta-aromatic group-4-estraene and acid additive salt application in medicine SCHERING AG (DE) 1996-10-16 CN disclosed
CN-1033033-C 11 beta, 19 bridged steroids having progesterone antagonistic activity SCHERING AG (DE) 1996-10-16 CN disclosed
US-5426102-A Antigestagenic, antiandrogenic, antiglucocorticoid, antimineralcorticoid properties SCHERING AKTIENGESELLSCHAFT (DE) 1995-06-20 US disclosed
CN-1074910-A D-height-(16-alkene)-11 beta-aryl-4-estrenes, its preparation method and do the application of medicine SCHERING AG (DE) 1993-08-04 CN disclosed
CN-1048219-A 11 beta-aryl-4-estrene pharmaceutical composition and process for preparing same SCHERING AG (DE) 1991-01-02 CN disclosed
CN-88102162-A 19, 11 beta-bridged steroids, their production and pharmaceutical preparations thereof 1988-11-23 CN disclosed