Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24507682 | 0.80 | TSHR (0.50) | TSHR | |
| SCHEMBL6618293 | 0.77 | — | — | |
| SCHEMBL12081199 | 0.76 | TSHR (0.59) | TSHR | |
| SCHEMBL75925 | 0.76 | TSHR (0.59) | TSHR | |
| SCHEMBL5176566 | 0.76 | TSHR (0.60) | TSHR | |
| SCHEMBL10646534 | 0.76 | TSHR (0.46) | TSHR | |
| SCHEMBL28218512 | 0.74 | TSHR (0.43) | TSHR | |
| SCHEMBL5454145 | 0.74 | TSHR (0.56) | TSHR | |
| SCHEMBL1349107 | 0.74 | TSHR (0.56) | TSHR | |
| SCHEMBL18526910 | 0.74 | TSHR (0.56) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623118-B1 | CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO WELLCOME SPA (IT) | 1998-05-13 | — | — | EP | disclosed |
| US-5486514-A | GASTRIN, CHOLECYSTOKININ RECEPTOR ANTAGONISTS | GLAXO SPA (IT) | 1996-01-23 | — | — | US | disclosed |
| EP-0623118-A1 | CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO S.p.A. (IT) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014075-A1 | CARBAMATE DERIVATIVES AND THEIR USE IN MEDICINE | GLAXO SPA (IT) | 1993-07-22 | — | — | WO | disclosed |