Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | FABP7 | O15540 | 2/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283053 | 0.82 | KMT2A (0.56) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL13712371 | 0.81 | KMT2A (0.58) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL28528205 | 0.81 | KMT2A (0.58) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL6380797 | 0.79 | KMT2A (0.62) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL7267676 | 0.79 | KMT2A (0.56) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL20825600 | 0.79 | KMT2A (0.56) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL19358192 | 0.79 | KMT2A (0.59) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL21332462 | 0.79 | KMT2A (0.66) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL30792907 | 0.78 | KMT2A (0.48) | KMT2AEPHX2CASP3FABP5FABP7 | |
| SCHEMBL30238049 | 0.77 | KMT2A (0.64) | KMT2AEPHX2CASP3FABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828737-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | disclosed |