Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 18/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620232 | 0.89 | DRD4 (0.51) | DRD4DRD2 | |
| SCHEMBL8618835 | 0.88 | DRD4 (0.51) | DRD4DRD3 | |
| SCHEMBL8619300 | 0.86 | DRD4 (0.45) | DRD4DRD2DRD3 | |
| SCHEMBL8618019 | 0.86 | DRD4 (0.52) | DRD4DRD2 | |
| SCHEMBL8616978 | 0.86 | DRD4 (0.52) | DRD4DRD2DRD3 | |
| SCHEMBL8622621 | 0.81 | KMT2A (0.52) | — | |
| SCHEMBL7498678 | 0.77 | DRD4 (0.57) | DRD4DRD2DRD3HRH3SMN1; SMN2 | |
| SCHEMBL7498674 | 0.77 | DRD4 (0.56) | DRD4DRD2DRD3HRH3SMN1; SMN2 | |
| SCHEMBL8709993 | 0.76 | DRD4 (0.45) | DRD4DRD3 | |
| SCHEMBL8708425 | 0.75 | DRD4 (0.48) | DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |