SCHEMBL8621826

SCHEMBL8621826

FC(F)(F)C(F)(F)CCCSCCI

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5526583 0.87 ESR1 (0.34) ESR1ESR2
SCHEMBL5523162 0.77 ESR1 (0.35) ESR1ESR2
SCHEMBL5854251 0.77 TDP1 (0.46) ESR1ESR2
SCHEMBL5166905 0.77 ESR1 (0.33) ESR1ESR2
SCHEMBL7798054 0.76 ESR1 (0.32) ESR1ESR2
SCHEMBL2348807 0.76 ESR1 (0.35) ESR1ESR2
SCHEMBL9578948 0.74 CES1 (0.47) ESR1ESR2
SCHEMBL19578784 0.74 CES1 (0.47) ESR1ESR2
SCHEMBL4729293 0.74 ESR1 (0.34) ESR1ESR2
SCHEMBL7593649 0.74 ESR1 (0.34) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807899-A Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents SCHERING AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
EP-0839130-A1 TRIPHENYL ETHYLENES WITH ANTI-OESTROGENIC PROPERTIES SCHERING AKTIENGESELLSCHAFT (DE) 1998-05-06 EP disclosed
WO-1997003046-A1 TRIPHENYL ETHYLENES WITH ANTI-OESTROGENIC PROPERTIES SCHERING AKTIENGESELLSCHAFT (DE) 1997-01-30 WO disclosed