Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621949 | 1.00 | HIF1A (0.49) | HIF1AMRGPRX4FFAR4FFAR1ANO1 | |
| SCHEMBL8624128 | 0.91 | HIF1A (0.48) | HIF1AMRGPRX4 | |
| SCHEMBL8372755 | 0.91 | HIF1A (0.48) | HIF1AMRGPRX4 | |
| SCHEMBL8372754 | 0.91 | HIF1A (0.48) | HIF1AMRGPRX4 | |
| SCHEMBL8617210 | 0.90 | MRGPRX4 (0.51) | HIF1AMRGPRX4 | |
| SCHEMBL8617209 | 0.90 | MRGPRX4 (0.51) | HIF1AMRGPRX4 | |
| SCHEMBL8617228 | 0.90 | HIF1A (0.53) | HIF1AMRGPRX4FFAR4FFAR1ANO1 | |
| SCHEMBL8617226 | 0.90 | HIF1A (0.53) | HIF1AMRGPRX4FFAR4FFAR1ANO1 | |
| SCHEMBL8589674 | 0.90 | HIF1A (0.50) | HIF1AMRGPRX4FFAR4FFAR1 | |
| SCHEMBL8623269 | 0.90 | HIF1A (0.50) | HIF1AMRGPRX4FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5523454-A | FUNGICIDES, PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-04 | — | — | US | disclosed |
| US-5516804-A | FUNGICIDES FOR PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |
| US-5395854-A | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |