Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.33 |
| ▸ | PPP5C | P53041 | 1/20 | 0.33 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291511 | 0.83 | TDP1 (0.46) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL6633941 | 0.82 | TDP1 (0.33) | MAPK1TDP1GAAHPGD | |
| SCHEMBL8920552 | 0.80 | TDP1 (0.40) | TP53CYP1A2TDP1PTPN1HPGD | |
| SCHEMBL8922321 | 0.80 | TDP1 (0.40) | TP53CYP1A2TDP1PTPN1HPGD | |
| SCHEMBL8920841 | 0.80 | TDP1 (0.40) | TP53CYP1A2TDP1PTPN1HPGD | |
| SCHEMBL8920942 | 0.80 | TDP1 (0.40) | TP53CYP1A2TDP1PTPN1HPGD | |
| SCHEMBL8920526 | 0.80 | TDP1 (0.40) | TP53CYP1A2TDP1PTPN1HPGD | |
| SCHEMBL28137355 | 0.77 | GAA (0.50) | MAPK1MAPTGAAHPGD | |
| SCHEMBL1481003 | 0.75 | TP53 (0.36) | MAPK1TP53CYP3A4HIF1ALMNA | |
| SCHEMBL16592474 | 0.74 | TDP1 (0.31) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608132-B1 | Coating varnish composition and antifouling coating composition | HITACHI CHEMICAL CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5439511-A | Composition containing polymer obtained by polymerizing unsaturated acid anhydride and another unsaturated compound, specified additive | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1995-08-08 | — | — | US | disclosed |