Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622532 | 1.00 | BCHE (0.42) | BCHESLC29A1EGFRERBB2NT5E | |
| SCHEMBL21367453 | 0.87 | SLC29A1 (0.43) | BCHESLC29A1EGFRERBB2NT5E | |
| SCHEMBL12580037 | 0.87 | SLC29A1 (0.43) | BCHESLC29A1EGFRERBB2NT5E | |
| SCHEMBL8621079 | 0.87 | SLC29A1 (0.43) | BCHESLC29A1EGFRERBB2NT5E | |
| SCHEMBL8621084 | 0.87 | SLC29A1 (0.43) | BCHESLC29A1EGFRERBB2NT5E | |
| SCHEMBL8621820 | 0.85 | SLC29A1 (0.46) | BCHESLC29A1NT5E | |
| SCHEMBL8621824 | 0.85 | SLC29A1 (0.46) | BCHESLC29A1NT5E | |
| SCHEMBL8624690 | 0.85 | NT5E (0.45) | BCHESLC29A1NT5EADORA3ADORA1 | |
| SCHEMBL8624686 | 0.85 | NT5E (0.45) | BCHESLC29A1NT5EADORA3ADORA1 | |
| SCHEMBL8618561 | 0.85 | EGFR (0.45) | BCHESLC29A1EGFRERBB2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817799-A | 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0540686-B1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5336764-A | 2'-fluorofuranosyl derivatives and novel method of preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-08-09 | — | — | US | disclosed |