SCHEMBL8622735

SCHEMBL8622735

O=C=NC(O)(COCCO)N=C=O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626457 0.96 MEN1 (0.42) TSHRMAPK1MEN1KMT2A
SCHEMBL11342630 0.96 MEN1 (0.42) TSHRMAPK1MEN1KMT2A
SCHEMBL3262161 0.73
SCHEMBL620462 0.69
SCHEMBL11287626 0.67
SCHEMBL4274503 0.67 CYP4F2 (0.31)
SCHEMBL8565164 0.64 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL17594569 0.64 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL6035495 0.64 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL2723111 0.64 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025078573-A1 PHOTOPROTECTIVE COSMETIC COMPOSITION UVE (FR) 2025-04-17 WO disclosed
CN-119212803-A Method for producing multilayer coating film 日涂工业涂料有限公司 2024-12-27 CN disclosed
WO-2024142550-A1 COATING COMPOSITION 日本ペイント・インダストリアルコーティングス株式会社 2024-07-04 WO disclosed
WO-2024142551-A1 METHOD FOR PRODUCING MULTILAYER COATING FILM 日本ペイント・インダストリアルコーティングス株式会社 2024-07-04 WO disclosed
WO-2024142549-A1 METHOD FOR PRODUCING MULTILAYER COATING FILM 日本ペイント・インダストリアルコーティングス株式会社 2024-07-04 WO disclosed
CN-118253464-A Method for producing multilayer coating film 日涂工业涂料有限公司 2024-06-28 CN disclosed
CN-117203252-A Process for preparing isocyanate group-terminated polyoxazolidone compositions 科思创德国股份有限公司 2023-12-08 CN disclosed
WO-2023203829-A1 METHOD FOR MANUFACTURING DOUBLE-LAYERED COATING FILM 日本ペイント・インダストリアルコーティングス株式会社 2023-10-26 WO disclosed
CN-114667185-A Method for producing microspheres 株式会社德山 2022-06-24 CN disclosed
EP-3959251-A1 LATENT REACTIVE ADHESIVE PREPARATIONS Covestro Intellectual Property GmbH & Co. KG (DE) 2022-03-02 EP disclosed
EP-0452681-B1 Electrostatographic imaging member containing polyarylamine polymers XEROX CORP (US) 1998-06-03 EP disclosed
EP-0452682-B1 Polyarylamine polymers XEROX CORP (US) 1997-09-17 EP disclosed
US-5155200-A Polyurethanes from dihydroxyarylamine compounds XEROX CORPORATION (US) 1992-10-13 US disclosed
EP-0452682-A2 Polyarylamine polymers XEROX CORPORATION (US) 1991-10-23 EP disclosed
EP-0452681-A2 Systems utilizing polyarylamine polymers XEROX CORPORATION (US) 1991-10-23 EP disclosed
US-5030532-A Electrophotographic imaging member utilizing polyarylamine polymers XEROX CORPORATION (US) 1991-07-09 US disclosed