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SCHEMBL8623147

SCHEMBL8623147

CC(NC(=O)CC(CC(=O)O)C(=O)O)C(Cc1ccc(Cl)c(Cl)c1)c1ccc(-c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FDFT1 P37268 9/20 1.00
▸ MEN1 O00255 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ KMO O15229 1/20 0.41
▸ CNR1 P21554 3/20 0.40
▸ FPR2 P25090 1/20 0.40
▸ CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8622842 1.00 FDFT1 (1.00) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8626967 0.91 FDFT1 (0.84) FDFT1MEN1KMT2ACNR1CNR2
SCHEMBL8620980 0.90 FDFT1 (0.82) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8625596 0.90 FDFT1 (0.82) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8623004 0.89 FDFT1 (1.00) FDFT1CNR1CNR2
SCHEMBL8619157 0.89 FDFT1 (1.00) FDFT1CNR1CNR2
SCHEMBL8621720 0.89 FDFT1 (1.00) FDFT1CNR1CNR2
SCHEMBL8625283 0.88 FDFT1 (1.00) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8622950 0.88 FDFT1 (0.79) FDFT1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL8622542 0.87 FDFT1 (0.78) FDFT1MEN1KMT2ACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5777150-A Substituted amic acid derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-07-07 — — US disclosed