Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 8/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8840182 | 0.88 | FFAR1 (0.53) | FFAR1PPARGPPARAALDH1A1GAA | |
| SCHEMBL8839946 | 0.87 | FFAR1 (0.52) | FFAR1PPARGPPARAGAATSHR | |
| SCHEMBL8839591 | 0.87 | FFAR1 (0.57) | FFAR1PPARGPPARAGAATSHR | |
| SCHEMBL8839967 | 0.86 | FFAR1 (0.56) | FFAR1PPARGPPARAALDH1A1GAA | |
| SCHEMBL4748088 | 0.84 | FFAR1 (0.59) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL7157649 | 0.84 | FFAR1 (0.59) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL13542481 | 0.83 | PPARG (0.62) | FFAR1PPARGPPARAKMT2A | |
| SCHEMBL8840010 | 0.83 | FFAR1 (0.64) | FFAR1PPARGPPARAGAATSHR | |
| SCHEMBL8839942 | 0.82 | FFAR1 (0.52) | FFAR1PPARGPPARAGAATSHR | |
| SCHEMBL8840045 | 0.82 | FFAR1 (0.52) | FFAR1PPARGPPARAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789570-A4 | ORAL HYPOGLYCEMIC AGENTS | LILLY CO ELI (US) | 1998-09-30 | — | — | EP | disclosed |
| EP-0789570-A1 | ORAL HYPOGLYCEMIC AGENTS | ELI LILLY AND COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5641796-A | PHENYL-OXAZOLYL-ALKYLOXY OR THIO-PHENYLALKYL TRIAZOLINE-3-ONE OR THIONE ANTIDIABETIC AGENT | ELI LILLY AND COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| WO-1996013264-A1 | ORAL HYPOGLYCEMIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |