Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 4/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623360 | 1.00 | ALB (0.41) | ALBTLR7DNMT1ADRB1TK1 | |
| SCHEMBL8617842 | 0.88 | ALB (0.40) | ALBTLR7DNMT1ADRB1NT5E | |
| SCHEMBL8617835 | 0.88 | ALB (0.40) | ALBTLR7DNMT1ADRB1NT5E | |
| SCHEMBL3195379 | 0.88 | ALB (0.55) | ALBTLR7DNMT1ADRB1LMNA | |
| SCHEMBL8621829 | 0.88 | ALB (0.55) | ALBTLR7DNMT1ADRB1LMNA | |
| SCHEMBL13871553 | 0.88 | ALB (0.55) | ALBTLR7DNMT1ADRB1LMNA | |
| SCHEMBL14577836 | 0.88 | ALB (0.55) | ALBTLR7DNMT1ADRB1LMNA | |
| SCHEMBL4129272 | 0.88 | ALB (0.55) | ALBTLR7DNMT1ADRB1LMNA | |
| SCHEMBL8617580 | 0.87 | ALB (0.41) | ALBTLR7DNMT1ADRB1TK1 | |
| SCHEMBL8622667 | 0.87 | ALB (0.41) | ALBTLR7DNMT1ADRB1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817799-A | 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0540686-B1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5336764-A | 2'-fluorofuranosyl derivatives and novel method of preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-08-09 | — | — | US | disclosed |