Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622264 | 0.93 | HSP90AA1 (0.41) | HSP90AA1CRHBPCRHR2NCEH1TSHR | |
| SCHEMBL8622309 | 0.89 | HSP90AA1 (0.42) | HSP90AA1CRHBPCRHR2NCEH1TSHR | |
| SCHEMBL8620764 | 0.84 | HSP90AA1 (0.39) | HSP90AA1CRHBPCRHR2NCEH1TSHR | |
| SCHEMBL8621618 | 0.84 | KDM4E (0.35) | NCEH1KMT2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL8623627 | 0.81 | HSP90AA1 (0.42) | HSP90AA1CRHBPCRHR2NCEH1TSHR | |
| SCHEMBL8617767 | 0.80 | HSP90AA1 (0.42) | HSP90AA1CRHBPCRHR2NCEH1TSHR | |
| SCHEMBL8621438 | 0.77 | MAPT (0.41) | CRHBPCRHR2MAPTKMT2AMEN1 | |
| SCHEMBL8622260 | 0.77 | HSP90AA1 (0.45) | HSP90AA1CRHBPCRHR2NCEH1TSHR | |
| SCHEMBL8624756 | 0.76 | KDM4E (0.36) | NCEH1KMT2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL8622167 | 0.76 | MAPT (0.35) | MAPTKMT2AMEN1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |