Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624756 | 0.91 | KDM4E (0.36) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL8617884 | 0.88 | ACP3 (0.36) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL8621618 | 0.88 | KDM4E (0.35) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL8619487 | 0.82 | KDM4E (0.37) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL7357998 | 0.82 | CA12 (0.48) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL8622309 | 0.82 | HSP90AA1 (0.42) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL8623668 | 0.79 | HPGD (0.47) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL8624752 | 0.74 | HPGD (0.47) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL8622264 | 0.73 | HSP90AA1 (0.41) | KDM4ENCEH1CA12CA2MMP2 | |
| SCHEMBL8620764 | 0.71 | HSP90AA1 (0.39) | NCEH1HPGDLMNAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |