Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 9/20 | 1.00 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | FABP2 | P12104 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625283 | 0.91 | FDFT1 (1.00) | FDFT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8625596 | 0.88 | FDFT1 (0.82) | FDFT1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8620980 | 0.88 | FDFT1 (0.82) | FDFT1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8619497 | 0.88 | FDFT1 (0.78) | FDFT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8619622 | 0.85 | FDFT1 (0.74) | FDFT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8622927 | 0.83 | FDFT1 (0.71) | FDFT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8620725 | 0.82 | FDFT1 (0.84) | FDFT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8619482 | 0.82 | FDFT1 (0.68) | FDFT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8619479 | 0.82 | FDFT1 (0.68) | FDFT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8623886 | 0.80 | FDFT1 (0.65) | FDFT1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777150-A | Substituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |