Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601881 | 1.00 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL21418866 | 1.00 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL29100475 | 1.00 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL30601880 | 1.00 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL8624075 | 1.00 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL1527211 | 0.91 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL1527213 | 0.91 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL12150807 | 0.91 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL12300482 | 0.91 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL12031300 | 0.91 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116814595-B | Adenosine deaminase mutant and immobilization thereof | 江苏申基生物科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-116814595-A | Adenosine deaminase mutant and immobilization thereof | 江苏申基生物科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| US-5773603-A | ADENOSINE DEAMINASE INHIBITOR | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| US-5705491-A | Adenosine deaminase inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0601322-A2 | Adenosindeaminase inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0269574-B1 | NOVEL ADENOSINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS AN ACTIVE INGREDIENT | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4843066-A | HYPOTENSIVE AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |