Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622167 | 0.93 | MAPT (0.35) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8622978 | 0.92 | MAPT (0.43) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8616781 | 0.92 | MAPT (0.38) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8618782 | 0.91 | HPGD (0.35) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8617973 | 0.87 | MAPT (0.38) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL27461620 | 0.86 | MAPT (0.42) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8620840 | 0.85 | MAPT (0.39) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8621438 | 0.85 | MAPT (0.41) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8616429 | 0.84 | MAPT (0.42) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8618866 | 0.83 | MAPT (0.45) | MAPTALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |