SCHEMBL8624140

SCHEMBL8624140

CC(Br)C(=O)NS(C)(=O)=O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 3/20 0.41
CXCR1 P25024 2/20 0.41
CA2 P00918 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
CXCL8 P10145 1/20 0.34
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4070679 0.79 NPSR1 (0.48) CXCR2CXCR1CA2NPSR1CXCL8
SCHEMBL18630360 0.75 DPP4 (0.41) CXCR2CXCR1CA2NPSR1CXCL8
SCHEMBL21966974 0.75 CXCR2 (0.41) CXCR2CXCR1CA2NPSR1CXCL8
SCHEMBL11148654 0.75 CXCR2 (0.41) CXCR2CXCR1CA2NPSR1CXCL8
SCHEMBL26452085 0.75 CXCR2 (0.41) CXCR2CXCR1CA2NPSR1CXCL8
SCHEMBL5662647 0.71 CXCR2 (0.39) CXCR2CXCR1CA2NPSR1CXCL8
SCHEMBL12430263 0.71 CXCR2 (0.42) CXCR2CXCR1CA2AKR1C3AKR1C2
SCHEMBL27261491 0.71 CXCR2 (0.42) CXCR2CXCR1CA2AKR1C3AKR1C2
SCHEMBL27261487 0.71 CXCR2 (0.42) CXCR2CXCR1CA2AKR1C3AKR1C2
SCHEMBL13592820 0.70 CXCR2 (0.37) CXCR2CXCR1CA2NPSR1CXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530511-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1998-06-03 EP disclosed
EP-0534283-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1997-12-17 EP disclosed
US-5422238-A Contains methine compound FUJI PHOTO FILM CO., LTD. (JP) 1995-06-06 US disclosed
US-5290676-A Methine dye sensitizers, controlling size and shape of silver halide grains FUJI PHOTO FILM CO., LTD. (JP) 1994-03-01 US disclosed
EP-0281103-B1 PHENOXYCARBOXYLIC ACID COMPOUNDS AND HERBICIDE COMPRISING IT AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1993-06-23 EP disclosed
EP-0534283-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-03-31 EP disclosed
EP-0530511-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-03-10 EP disclosed
US-5084085-A Plant growth regulators FMC CORPORATION (US) 1992-01-28 US disclosed
EP-0322413-A4 HERBICIDES. FMC CORP (US) 1989-10-04 EP disclosed
EP-0322413-A1 HERBICIDES FMC Corporation (US) 1989-07-05 EP disclosed
US-4845264-A PRE- AND POST-EMERGENCE FOR BROAD-LEAVED WEEDS TEIJIN LIMITED (JP) 1989-07-04 US disclosed
CN-1032005-A Weedicide FMC CO LTD (US) 1989-03-29 CN disclosed
EP-0281103-A2 Phenoxycarboxylic acid compounds and herbicide comprising it as active ingredient TEIJIN LIMITED (JP) 1988-09-07 EP disclosed
WO-1988001133-A1 HERBICIDES FMC CORPORATION (US) 1988-02-25 WO disclosed