Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.35 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621697 | 0.87 | GRIK1 (0.38) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8621635 | 0.86 | KDM4D (0.35) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8621605 | 0.84 | PARP1 (0.42) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL3680141 | 0.84 | GRIK1 (0.53) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8617971 | 0.84 | SIRT2 (0.40) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8623608 | 0.84 | GRIK1 (0.38) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8620598 | 0.82 | GRIN2D (0.35) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8623703 | 0.81 | PDE9A (0.32) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8624742 | 0.73 | GRIK1 (0.38) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8618027 | 0.72 | PARP1 (0.36) | GRIA1GRIA2GRIA3GRIA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| EP-0696289-A1 | BENZO F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |