Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624450 | 0.89 | KDM4E (0.58) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL8628381 | 0.82 | KDM4E (0.47) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL8627300 | 0.78 | KDM4E (0.60) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL14564811 | 0.77 | KDM4E (0.66) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL9773672 | 0.76 | KCNH2 (0.55) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL4364273 | 0.74 | KCNH2 (0.55) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL9078435 | 0.74 | KDM4E (0.66) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL5792882 | 0.74 | GSK3B (0.55) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL27002955 | 0.74 | KDM4E (0.74) | KDM4EHPGDALDH1A1KCNH2HSD17B10 | |
| SCHEMBL9731260 | 0.73 | TOP2A (0.55) | KDM4EHPGDALDH1A1KCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776948-A | BACTERICIDE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0664288-A1 | FLUOROQUINOLINE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-07-26 | — | — | EP | disclosed |