Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27602612 | 0.92 | CYP19A1 (0.52) | CYP19A1MAPTHRH4MEN1KMT2A | |
| SCHEMBL28923795 | 0.83 | KCNH2 (0.50) | CYP19A1MAPTHRH4MEN1KMT2A | |
| SCHEMBL10430003 | 0.83 | CYP19A1 (0.48) | CYP19A1MAPTHRH4ALDH1A1PKM | |
| SCHEMBL28007741 | 0.82 | CYP19A1 (0.54) | CYP19A1MAPTHRH4MEN1KMT2A | |
| SCHEMBL9486575 | 0.81 | CYP19A1 (0.49) | CYP19A1MAPTHRH4MEN1KMT2A | |
| SCHEMBL8802605 | 0.81 | CYP19A1 (0.49) | CYP19A1MAPTHRH4L3MBTL1ALDH1A1 | |
| SCHEMBL6597520 | 0.81 | CYP19A1 (0.51) | CYP19A1MAPTHRH4MEN1KMT2A | |
| SCHEMBL7807147 | 0.78 | KDM4E (0.55) | CYP19A1MAPTHRH4MEN1KMT2A | |
| SCHEMBL5828718 | 0.78 | CYP19A1 (0.54) | CYP19A1MAPTHRH4MEN1KMT2A | |
| SCHEMBL1122113 | 0.77 | FFAR1 (0.49) | CYP19A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885235-A1 | NUCLEOSIDE ANALOGUES | Amersham Pharmacia Biotech UK Limited (GB) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997028176-A1 | NUCLEOSIDE ANALOGUES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |