SCHEMBL8624616

SCHEMBL8624616

C[Si](C)(C)O[Si](C)(CCCNC1CCCCC1)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 11/20 0.40
KDM4E B2RXH2 1/20 0.40
CXCL12 P48061 1/20 0.39
HRH4 Q9H3N8 5/20 0.37
HRH3 Q9Y5N1 5/20 0.37
OPRL1 P41146 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30423000 0.86 CXCR4 (0.40) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL773610 0.84 CXCR4 (0.41) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL10400141 0.82 CXCR4 (0.41) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL778037 0.81 CXCR4 (0.39) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL30866491 0.81 CXCR4 (0.36) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL15360597 0.79 CXCR4 (0.41) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL32678344 0.77 CXCR4 (0.41) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL15360810 0.77 CXCR4 (0.39) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL4522392 0.77 CXCR4 (0.46) CXCR4KDM4ECXCL12HRH4HRH3
SCHEMBL18692027 0.77 CXCR4 (0.46) CXCR4KDM4ECXCL12HRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705589-A Organosilane and organopolysiloxane free radical initiators and macromonomers and graft copolymers which can be prepared with them WACKER-CHEMIE GMBH (DE) 1998-01-06 US disclosed
EP-0696608-B1 Organosilane and organopolysiloxane radical initiators and macromonomers and graft-copolymers prepared therefrom WACKER CHEMIE GMBH (DE) 1996-12-11 EP disclosed
US-5548070-A Organosilicon compounds having triazene groups WACKER-CHEMIE GMBH (DE) 1996-08-20 US disclosed
EP-0696608-A1 Organosilane and organopolysiloxane radical initiators and macromonomers and greft-copolymers prepared therefrom Wacker-Chemie GmbH (DE) 1996-02-14 EP disclosed
EP-0635534-B1 Organosilicon compounds with triazene units WACKER CHEMIE GMBH (DE) 1995-12-06 EP disclosed
EP-0635534-A1 Organosilicon compounds with triazene units Wacker-Chemie GmbH (DE) 1995-01-25 EP disclosed