Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.73 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.64 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.64 |
| ▸ | DHODH | Q02127 | 3/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313257 | 0.88 | PKN1 (0.74) | PARP1PKN1PKN2DHODHPLA2G2A | |
| SCHEMBL1891860 | 0.86 | PARP1 (0.80) | PARP1DHODHPIN1 | |
| Acetic Acid SCHEMBL7316877 | 0.85 | PKN1 (0.69) | PARP1PKN1PKN2DHODHPLA2G2A | |
| SCHEMBL7317874 | 0.85 | PARP1 (1.00) | PARP1PKN1PKN2DHODH | |
| SCHEMBL7322715 | 0.83 | PKN1 (0.81) | PARP1PKN1PKN2DHODHPLA2G2A | |
| SCHEMBL1170810 | 0.81 | PKN1 (0.77) | PARP1PKN1PKN2DHODHPLA2G2A | |
| SCHEMBL12673092 | 0.81 | PARP1 (0.66) | PARP1PKN1PKN2DHODHPIN1 | |
| SCHEMBL505325 | 0.81 | PKN1 (0.77) | PARP1PKN1PKN2DHODHPLA2G2A | |
| SCHEMBL12673126 | 0.81 | PARP1 (0.68) | PARP1PKN1PKN2DHODHPIN1 | |
| SCHEMBL12673377 | 0.80 | PARP1 (0.67) | PARP1PKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841924-A1 | BENZIMIDAZOLE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997004771-A1 | BENZIMIDAZOLE COMPOUNDS | NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) | 1997-02-13 | — | — | WO | disclosed |