⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648350 | 0.86 | — | — | |
| SCHEMBL3289774 | 0.86 | — | — | |
| SCHEMBL9406314 | 0.85 | CYP1A2 (0.39) | — | |
| SCHEMBL13745508 | 0.85 | — | — | |
| SCHEMBL9406311 | 0.85 | CYP1A2 (0.39) | — | |
| SCHEMBL11976830 | 0.83 | CYP1A2 (0.48) | — | |
| SCHEMBL1581527 | 0.83 | — | — | |
| SCHEMBL14402870 | 0.83 | CYP1A2 (0.48) | — | |
| SCHEMBL7741201 | 0.83 | CYP1A2 (0.48) | — | |
| SCHEMBL7733510 | 0.83 | CYP1A2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070275-A | Heterocyclic compound and application thereof | 成都麻沸散医药科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122036604-A | Compound and application thereof | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-120058697-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2025-05-30 | — | — | CN | disclosed |
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-2024129763-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-116003409-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-107207493-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115583947-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-10 | — | — | CN | disclosed |
| EP-3218375-B1 | SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH INC (US) | 2022-04-27 | — | — | EP | disclosed |
| US-20210277003-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-09 | — | — | US | disclosed |
| WO-2004000811-A1 | ARYLSULFONYLHYDROXAMIC ACID AND AMIDE DERIVATIVES AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-12-31 | — | — | WO | disclosed |
| US-20030162800-A1 | Tricyclic 2-pyrimidone compounds useful as HIV reverse transcriptase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2003-08-28 | — | — | US | disclosed |
| WO-2003062238-A1 | TRICYCLIC 2-PYRIMIDONE COMPOUNDS USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-31 | — | — | WO | disclosed |
| US-6596729-B2 | Especially in combination with one or more HIV reverse transcriptase inhibitors, HIV protease inhibitors, fusion inhibitors, and/or CCR-5 | BRISTOL-MYERS SQUIBB COMPANY | 2003-07-22 | — | — | US | disclosed |
| EP-1303515-A2 | TRICYCLIC 2-PYRIDONE COMPOUNDS USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-04-23 | — | — | EP | disclosed |
| US-20020107261-A1 | Tricyclic-2-pyridone compounds useful as HIV reverse transcriptase inhibitors | DUPONT PHARMACEUTICALS COMPANY | 2002-08-08 | — | — | US | disclosed |
| WO-2002008226-A2 | TRICYCLIC 2-PYRIDONE COMPOUNDS USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-31 | — | — | WO | disclosed |
| EP-0173462-B1 | ELLIPTICINE DERIVATIVE AND PRODUCTION PROCESS THEREOF | SUNTORY LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |
| US-4698423-A | ANTITUMOR AGENTS | SUNTORY LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0173462-A2 | Ellipticine derivative and production process thereof | SUNTORY LIMITED (JP) | 1986-03-05 | — | — | EP | disclosed |