Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170794 | 0.82 | HPRT1 (0.51) | HPRT1TYMP | |
| SCHEMBL16038272 | 0.82 | HPRT1 (0.51) | HPRT1TYMP | |
| SCHEMBL4748185 | 0.80 | ENPP1 (0.36) | ENPP1 | |
| SCHEMBL4748203 | 0.80 | HPRT1 (0.36) | HPRT1CYP3A4ENPP1 | |
| SCHEMBL8933964 | 0.76 | HPRT1 (0.35) | HPRT1 | |
| SCHEMBL886934 | 0.69 | PDPK1 (0.40) | HPRT1CYP3A4TYMP | |
| SCHEMBL16037330 | 0.69 | PDPK1 (0.40) | HPRT1CYP3A4TYMP | |
| SCHEMBL6897604 | 0.68 | CYP3A4 (0.46) | HPRT1CYP3A4TYMP | |
| SCHEMBL3478592 | 0.67 | CDK1 (0.50) | — | |
| Hypophosphorous Acid SCHEMBL3803586 | 0.66 | PDPK1 (0.37) | HPRT1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10076532-B2 | Acyclic nucleoside phosphonate diesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-18 | — | — | US | disclosed |
| US-20170304330-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-26 | — | — | US | disclosed |
| US-5763424-A | SEQUESTERING AGENT | GILEAD SCIENCES, INC. (US) | 1998-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10076532-B2 | Acyclic nucleoside phosphonate diesters | NTPCR, PNP, TYMP | HPRT1 57/4885CYP3A4 3422/4885TYMP 3/4885 |
| US-20170304330-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | HPRT1 57/4885CYP3A4 3422/4885TYMP 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.