SCHEMBL86250

SCHEMBL86250

CNCC1(C)CC(NC(=O)O)CC(C)(C)C1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.31
POLB P06746 2/20 0.31
ALDH1A1 P00352 1/20 0.31
KDM4E B2RXH2 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13199418 0.87 TSHR (0.64) TSHRTDP1HTTPOLBALDH1A1
SCHEMBL10203832 0.84 TSHR (0.61) TSHRTDP1HTTPOLBALDH1A1
SCHEMBL14115815 0.84 TSHR (0.54) TSHRTDP1HTTPOLBALDH1A1
SCHEMBL25825573 0.84 TSHR (0.78) TSHRTDP1ALDH1A1
SCHEMBL20086243 0.84 TSHR (0.64) TSHRTDP1ALDH1A1KMT2A
SCHEMBL15242160 0.83 TSHR (0.51) TSHRHTTPOLBALDH1A1KDM4E
SCHEMBL13009631 0.83 TSHR (0.52) TSHRTDP1
SCHEMBL12230721 0.83 TSHR (0.59) TSHRTDP1ALDH1A1GAA
SCHEMBL86232 0.82 TSHR (0.50) TSHRHTTPOLBALDH1A1KDM4E
Hydrochloric Acid SCHEMBL15105140 0.82 TSHR (0.58) TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8945441-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2015-02-03 US disclosed
US-20140131915-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2014-05-15 US disclosed
US-8662878-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2014-03-04 US disclosed
US-20130202729-A1 Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2013-08-08 US disclosed
US-8439666-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2013-05-14 US disclosed
US-20120189728-A1 METHODS AND MATERIALS FOR FABRICATING LAMINATE NANOMOLDS AND NANOPARTICLES THEREFROM LIQUIDIA TECHNOLOGIES, INC. (US) 2012-07-26 US disclosed
US-8128393-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2012-03-06 US disclosed
US-20080131692-A1 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. 2008-06-05 US disclosed