Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.65 |
| ▸ | CA9 | Q16790 | 5/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | ALB | P02768 | 5/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620142 | 0.99 | CA12 (0.67) | CA12CA9CA4ALBMAOB | |
| SCHEMBL24589798 | 0.86 | CA12 (0.68) | CA12CA9CA4ALBMAOB | |
| SCHEMBL22501643 | 0.83 | CA12 (0.65) | CA12CA9CA4ALBMAOB | |
| SCHEMBL1034943 | 0.82 | CA12 (0.72) | CA12CA9CA4ALBMAOB | |
| SCHEMBL29673209 | 0.82 | CA12 (0.72) | CA12CA9CA4ALBMAOB | |
| SCHEMBL19382859 | 0.82 | CA12 (0.64) | CA12CA9CA4ALBMAOB | |
| SCHEMBL12989749 | 0.82 | CA12 (0.64) | CA12CA9CA4ALBMAOB | |
| SCHEMBL22501626 | 0.82 | CA9 (0.64) | CA12CA9CA4ALBMAOB | |
| SCHEMBL19026763 | 0.81 | CA12 (0.70) | CA12CA9CA4ALBMAOB | |
| SCHEMBL24590064 | 0.81 | CA12 (0.62) | CA12CA9CA4ALBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770710-A | REACTING METHYLTRITHIO ANTIBIOTIC LL-E32288 DERIVATIVE WITH MERCAPTAN COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| US-5606040-A | DERIVATIZED OLIGOSACCHARIDE ANTIBIOTICS WITH CHROMOPHORE | AMERICAN CYANAMID COMPANY (US) | 1997-02-25 | — | — | US | disclosed |