Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.45 |
| ▸ | BCL2 | P10415 | 6/20 | 0.43 |
| ▸ | BECN1 | Q14457 | 6/20 | 0.43 |
| ▸ | MIF | P14174 | 4/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371723 | 0.87 | CYP17A1 (0.46) | CYP17A1BCL2BECN1MIFPSMB8 | |
| SCHEMBL7371172 | 0.77 | MIF (0.62) | CYP17A1MIFHDAC6 | |
| SCHEMBL31341226 | 0.72 | KMT2A (0.54) | MIFKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1259192 | 0.72 | S1PR1 (0.51) | CYP17A1BCL2BECN1PSMB8KMT2A | |
| SCHEMBL20865536 | 0.70 | CYP17A1 (0.68) | CYP17A1PSMB8HDAC3HDAC1HDAC2 | |
| SCHEMBL13055402 | 0.68 | CYP17A1 (0.59) | CYP17A1PSMB8SMN1; SMN2 | |
| SCHEMBL6607121 | 0.66 | CYP17A1 (0.58) | CYP17A1PSMB8HDAC3HDAC1HDAC2 | |
| SCHEMBL4759920 | 0.66 | CYP17A1 (0.79) | CYP17A1BCL2BECN1PSMB8HDAC3 | |
| SCHEMBL26328838 | 0.65 | CYP17A1 (0.55) | CYP17A1BCL2BECN1PSMB8HDAC3 | |
| SCHEMBL18570243 | 0.65 | CYP17A1 (0.61) | CYP17A1BCL2BECN1PSMB8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |