Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842300 | 0.96 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL7842077 | 0.93 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL7842063 | 0.91 | EDNRB (0.57) | EDNRAEDNRB | |
| SCHEMBL7840661 | 0.90 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL8620747 | 0.90 | EDNRB (0.57) | EDNRAEDNRB | |
| SCHEMBL8619001 | 0.88 | EDNRB (0.55) | EDNRAEDNRB | |
| SCHEMBL7844620 | 0.87 | EDNRB (0.62) | EDNRAEDNRB | |
| SCHEMBL8703404 | 0.87 | EDNRB (0.56) | EDNRAEDNRB | |
| SCHEMBL7840944 | 0.87 | EDNRB (0.67) | EDNRAEDNRB | |
| SCHEMBL7831939 | 0.86 | EDNRB (0.61) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882030-A1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK PATENT GmbH (DE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997030982-A1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-08-28 | — | — | WO | disclosed |