SCHEMBL8626488

SCHEMBL8626488

CCCCCCCC/C=C/C(CC(CC(=O)O)C(=O)O)C(CC(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.44
TERT O14746 3/20 0.43
PTPN1 P18031 3/20 0.43
PPARG P37231 3/20 0.43
PPARD Q03181 3/20 0.43
PPARA Q07869 3/20 0.43
TOP1 P11387 3/20 0.43
MAPT P10636 2/20 0.43
BLM P54132 2/20 0.43
HSD17B10 Q99714 2/20 0.43
FABP4 P15090 2/20 0.43
GMNN O75496 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43
APEX1 P27695 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626494 1.00 EPHX2 (0.44) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL8355776 0.88 PLA2G10 (0.51) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL10786245 0.87 PLA2G10 (0.35) EPHX2PPARGTDP1PLA2G10
SCHEMBL14321582 0.85 PPARG (0.48) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL14321583 0.85 PPARG (0.48) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL28394357 0.85 PPARG (0.46) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL14321625 0.85 PPARG (0.48) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL3133696 0.85 PPARG (0.48) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL14321626 0.85 PPARG (0.48) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL3133699 0.85 PPARG (0.48) EPHX2TERTPTPN1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0128569-B1 ELECTROPHOTOGRAPHIC DEVELOPER COMPOSITION Kao Corporation (JP) 1987-10-28 EP claimed
EP-0128569-A2 Electrophotographic developer composition Kao Corporation (JP) 1984-12-19 EP claimed
US-5712074-A Toner for developing electrostatic latent image KAO CORPORATION (JP) 1998-01-27 US disclosed
US-5683845-A SMALL POLYTETRAFLUOROETHYLENE PARTICLES ON SURFACE OF TONER, POLYESTER BINDER KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0460665-B1 Toner composition KAO CORP (JP) 1997-09-03 EP disclosed
US-5424161-A Containing polyester resin KAO CORPORATION (JP) 1995-06-13 US disclosed
EP-0523733-B1 Electrostatic charge image developer composition KAO CORP (JP) 1995-03-15 EP disclosed
US-5258255-A Polyester binder resin; electrography; durability; cleaning blade not reversed or broken KAO CORPORATION (JP) 1993-11-02 US disclosed
EP-0523733-A1 Electrostatic charge image developer composition KAO CORPORATION (JP) 1993-01-20 EP disclosed
US-5154999-A Resin binder for toner composition KAO CORPORATION (JP) 1992-10-13 US disclosed
EP-0195604-B1 PRODUCTION OF POLYESTER AND TONER CONTAINING THE SAME Kao Corporation (JP) 1992-04-29 EP disclosed
EP-0460665-A1 Toner composition KAO CORPORATION (JP) 1991-12-11 EP disclosed
EP-0186307-B1 RESIN BINDER FOR TONER COMPOSITION Kao Corporation (JP) 1989-05-24 EP disclosed
US-4788122-A POLYESTER CONTAINING DIOL AND ACID COMPONENT WHICH IS A COPOLYMER OF STYRENE AND CARBOXYLIC VINYL MONOMER KAO CORPORATION (JP) 1988-11-29 US disclosed
EP-0128569-B1 ELECTROPHOTOGRAPHIC DEVELOPER COMPOSITION Kao Corporation (JP) 1987-10-28 EP disclosed
EP-0195604-A2 Production of polyester and toner containing the same Kao Corporation (JP) 1986-09-24 EP disclosed
EP-0186307-A2 Resin binder for toner composition Kao Corporation (JP) 1986-07-02 EP disclosed
US-4588668-A Polyester resin, electrophotographic developer composition KAO CORPORATION (JP) 1986-05-13 US disclosed
EP-0128569-A2 Electrophotographic developer composition Kao Corporation (JP) 1984-12-19 EP disclosed