Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29384964 | 1.00 | — | — | |
| Bromide SCHEMBL3460232 | 1.00 | — | — | |
| Bromide SCHEMBL5922799 | 1.00 | — | — | |
| Bromide SCHEMBL11509335 | 1.00 | — | — | |
| Bromide SCHEMBL9489791 | 1.00 | CA1 (0.50) | — | |
| Bromide SCHEMBL1775773 | 1.00 | — | — | |
| Bromide SCHEMBL5922792 | 1.00 | — | — | |
| Bromide SCHEMBL1257173 | 1.00 | — | — | |
| Bromide SCHEMBL720621 | 1.00 | — | — | |
| Bromide SCHEMBL180729 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272910-B1 | QUINOLINE COMPOUND | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-08-07 | — | — | EP | claimed |
| EP-0272910-A1 | Quinoline compound | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-06-29 | — | — | EP | claimed |
| EP-0847870-A1 | Dyes for a thermal transfer dye-donor recording sheet | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1998-06-17 | — | — | EP | disclosed |
| EP-0727323-A1 | Heat transfer sheet | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5517072-A | Method and apparatus for increasing the efficiency of electrical rotary machines | EFFICIENT PROPULSION, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0427867-B1 | THERMAL TRANSFER SHEET | DAINIPPON PRINTING CO LTD (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5304528-A | With sublimable dye having two chromophores; high density, storage stability, colorfastness | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0582324-A1 | Heat transfer sheet | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1994-02-09 | — | — | EP | disclosed |
| US-5223476-A | HEAT TRANSFER SHEET | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |
| US-5166160-A | Administering 6-piperidinocarbostyril or salt; congestive heart failure; cardiotonic and inotropic agents | BURROUGHS WELLCOME CO. (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0272910-B1 | QUINOLINE COMPOUND | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-08-07 | — | — | EP | disclosed |
| US-4118394-A | ANTIULCER, ANTIDEPRESSANT | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-10-03 | — | — | US | disclosed |
| US-4066763-A | Thiazinoindoles useful as antidepressants | AYERST MCKENNA AND HARRISON LTD. (CA) | 1978-01-03 | — | — | US | disclosed |
| US-4061617-A | ANTIOXIDANT, DIELECTRIC STABILIZERS, SEMICONDUCTORS, ION EXCHANGE RESINS | GENERAL ELECTRIC COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4056538-A | ANTIDEPRESSANTS, ANTIULCER AGENTS | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1977-11-01 | — | — | US | disclosed |
| US-4056537-A | CYCLIZATION, ACID CATALYST | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-11-01 | — | — | US | disclosed |
| US-4012511-A | ANTIULCER AGENTS | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-03-15 | — | — | US | disclosed |
| US-3995052-A | Indenopyran- and indenothiopyranalkylamines III in the treatment of depression | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-11-30 | — | — | US | disclosed |
| US-3962236-A | ANTIDEPRESSANTS, ANTI-ULCER | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-06-08 | — | — | US | disclosed |
| US-3959223-A | Oxidation-reduction diphenoquinone-diphenonhydroquinone polymers | GENERAL ELECTRIC COMPANY (US) | 1976-05-25 | — | — | US | disclosed |