Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.65 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 3/20 | 0.33 |
| ▸ | GABRD | O14764 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626747 | 1.00 | SLC7A5 (0.65) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL27600339 | 0.84 | SLC7A5 (0.59) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL27600338 | 0.84 | SLC7A5 (0.59) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL14060294 | 0.82 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL14060291 | 0.82 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL8915281 | 0.81 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL8915275 | 0.81 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| SCHEMBL497537 | 0.80 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 | |
| Valine SCHEMBL8516 | 0.79 | — | — | |
| Valine SCHEMBL288203 | 0.79 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830864-A | RIBONUCLEOTIDE REDUCTASE INHIBITOR | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 1998-11-03 | — | — | US | disclosed |
| EP-0560274-B1 | Antiherpes peptide derivatives having a ureido N-terminus | BOEHRINGER INGELHEIM CA LTD (CA) | 1998-06-24 | — | — | EP | disclosed |
| EP-0560274-A1 | Antiherpes peptide derivatives having a ureido N-terminus | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | disclosed |