Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120370 | 1.00 | UGT2B7 (0.48) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL30863856 | 0.83 | HSD17B10 (0.55) | UGT2B7MEN1KMT2AMMP9SLC6A2 | |
| SCHEMBL10077531 | 0.83 | HSD17B10 (0.55) | UGT2B7MEN1KMT2AMMP9SLC6A2 | |
| SCHEMBL31215092 | 0.83 | HSD17B10 (0.55) | UGT2B7MEN1KMT2AMMP9SLC6A2 | |
| SCHEMBL159191 | 0.83 | HSD17B10 (0.55) | UGT2B7MEN1KMT2AMMP9SLC6A2 | |
| SCHEMBL8120372 | 0.83 | UGT2B7 (0.50) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL2829819 | 0.83 | HSD17B10 (0.55) | UGT2B7MEN1KMT2AMMP9SLC6A2 | |
| SCHEMBL10821284 | 0.81 | UGT2B7 (0.48) | UGT2B7MEN1KMT2AATMMMP9 | |
| Hydrochloric Acid SCHEMBL11053399 | 0.80 | UGT2B7 (0.47) | UGT2B7MEN1KMT2AATMMMP9 | |
| SCHEMBL5280956 | 0.78 | HSD17B10 (0.53) | UGT2B7MEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801242-A | Process for making quinolonyl lactam antimicrobials and novel intermediate compounds | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-01 | — | — | US | disclosed |
| US-5703231-A | Process for making antimicrobial compounds | THE PROCTER & GAMBLE COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-4956358-A | ANTIBIOTICS, BACTERICIDES, CEPHALOSPORINS AND ISOCEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4906659-A | Antibiotic tan-749, its derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| US-4897489-A | 2-/5-OXO-2-TETRAHYDROFURANY4-3-OXOISOXOL-IDINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4891427-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| US-4876251-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| US-4851422-A | Antibiotic 2-(3-oxo-2-isoxazolidinyl)-5-oxo-2-tetrahydrofuran-carboxylates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0271829-A2 | Delta-hydroxy-beta-lysine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1988-06-22 | — | — | EP | disclosed |
| EP-0253337-A2 | Tricyclic cepham compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |
| EP-0249909-A1 | Tricyclic penam compounds, their production and their use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0250096-A1 | Isoxazolone derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |